Peptides - Calculate Indices and Theoretical Physicochemical Properties of Protein Sequences
Includes functions to calculate several physicochemical properties and indices for amino-acid sequences as well as to read and plot 'XVG' output files from the 'GROMACS' molecular dynamics package.
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bioinformaticscalculate-indicespeptidesprotein-sequencesqsarcpp
9.39 score 105 stars 7 dependents 294 scripts 1.2k downloadsSCORPION - Single Cell Oriented Reconstruction of PANDA Individually Optimized Networks
Constructs cell-type-specific gene regulatory networks from single-cell RNA-sequencing data. The method implements the SCORPION algorithm, which first aggregates individual cells into super-cells and then applies PANDA (Passing Attributes between Networks for Data Assimilation) to infer transcription factor-target regulatory relationships. It also provides statistical methods for differential edge analysis.
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cell-type-specificcomparative-edge-analysisgene-regulatory-networkpopulation-comparisonprotein-protein-interactionsingle-celltranscription-factorstranscriptomics
5.49 score 28 stars 20 scripts 632 downloadsrPanglaoDB - Download and Merge Single-Cell RNA-Seq Data from the PanglaoDB Database
Download and merge labeled single-cell RNA-seq data from the PanglaoDB <https://panglaodb.se/> into a Seurat object.
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data-integrationdata-miningrna-seqsingle-cellsingle-cell-rna-seq
4.51 score 27 stars 24 scripts 308 downloadsretriever - Generate Disease-Specific Response Signatures from the LINCS-L1000 Data
Generates disease-specific drug-response profiles that are independent of time, concentration, and cell-line. Based on the cell lines used as surrogates, the returned profiles represent the unique transcriptional changes induced by a compound in a given disease.
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2.22 score 11 scripts 242 downloads